Presented by: Sergey Sukhikh PhD
Moscow state university of medicine and dentistry named after A.I. Evdokimov

Introduction

Currently, suburethral slings are the standard of surgical treatment for stress urinary incontinence in women, which is very efficient, but also has several possible postoperative complications. Long-term performance of mid-urethral slings are scarcely studied.

Materials

The mid-urethral synthetic tape with tension control mechanism (MUS - TC) was developed as a polyvinyldinfluoride tape with absorbable collagen 5mm thick damping layer at mid-urethral part. A prospective randomized trial initiated in 2018 showed a high efficacy and safety profile of this device. In the analysis of the results one year after surgery, the efficiency of surgical treatment was 96%, the rate of postoperative complications, infravesical obstruction, was 2%, and the de novo urgency was 6%. In the present study we evaluated long-term outcomes (more than 5 years) by means of a telephone survey and validated questionnaires (UDI-6, IIQ-7) among patients who underwent MUS – TC. The study registered in ClinicalTrials.gov No. NCT04101279.

Results

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The average score on the UDI-6 survey was 1,22±0,81 and 1,2±0,77 on the IIQ-7 survey. There was a non-significant increase of scores after 60 months compared to 12 months after surgery. When analyzing individual clinical cases after 60 months, 10 patients noted worsening of symptoms. Of them, 6 patients noted recurrence of urinary incontinence when coughing or exercising. Accordingly, the subjective efficacy of surgical treatment during the 5-year follow-up period was 88%.

Conclusion

The efficacy and safety data in the mid-term follow-up of patients after MUS – TC are comparable with the worldwide data. However, further long-term follow-up of the patients is required.

Funding

no

Co-Authors

Roman Stroganov, PhD
Moscow state university of medicine and dentistry named after A.I. Evdokimov

Yuri Kupriyanov, PhD
Moscow state university of medicine and dentistry named after A.I. Evdokimov

Gevorg Kasyan, MD
Moscow state university of medicine and dentistry named after A.I. Evdokimov

Dmitry Pushkar, MD
Moscow state university of medicine and dentistry named after A.I. Evdokimov